Researchers at the Luxembourg Institute of Health are investigating a new approach to helping people who are allergic to cat dander, specifically, the major cat allergen Fel d 1.

Allergen-specific immunotherapy aims to provide long-term relief from allergies, but much remains to be learned about the therapy.

In a study published in December 2020 in the journal Allergy, researchers gave mice higher doses of a known immunomodulatory adjuvant called CpG than have been used in the past and also used a different administration route — subcutaneous injection, or under the skin.

All major hallmarks of allergy were reverted, leading the study authors to recommend further investigation of this promising treatment.